Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

VIT Business School

VIT Unitversity

Chennai Campus

Acta Tropica

In-vitro anti-inflammatory and mosquito larvicidal efficacy of nickel nanoparticles phytofabricated from aqueous leaf extracts of Aegle marmelos Correa

Emergence of antibiotic resistance by bacteria has become a serious threat for public health worldwide. In this study, Streptomyces isolated from fertile soil sample was tested for biosynthesis of silver nanoparticles (AgNps) using cell-free supernatant and synthesized AgNps were screened for anti-ESBL (extended spectrum b-lactamase) activity against multi-drug resistant (MDR) ESBL-producing strain Klebsiella pneumoniae (ATCC 700603) and other medically important pathogens. Synthesis of AgNps was confirmed by change in pale yellow color to dark brown color and characteristic absorption spectra at 420 nm. The XRD spectrum displayed typical peaks of crystalline silver and EDAX analysis showed a major signal for silver. FTIR spectra revealed prominent peaks at 3,294 cm-1 (NH stretching due to amide group), 2,952 cm-1 (aldehydic C-H stretching) 1,658 cm-1 indicating the presence of carbonyl group. AgNps were spherical in shape with size ranging from 20 to 70 nm. The synthesized AgNps showed significant antimicrobial activity against standard ESBL pathogen K. pneumoniae (22 mm), 21 mm against clinical ESBL isolate E. coli and 16 mm against clinical ESBL isolates K. pneumoniae and Citrobacter species, respectively. The results of this study suggest that AgNps synthesized by Streptomyces sp. VITSJK10 can be used as a potential alternative to control MDR ESBL pathogens. The present study aimed for green synthesis of AgNps using Streptomyces species and to explore its anti-ESBL activity. © Springer-Verlag 2013.

Department of Bio-Medical Sciences

School of Bio Sciences and Technology

Vellore Campus

Bioprocess and Biosystems Engineering

Anti-ESBL activity of silver nanoparticles biosynthesized using soil Streptomyces species

"Do acquisitions create value for the acquiring firm's shareholders?" This is an unresolved question in the literature of acquisitions. This study analyzes the value creation of acquirers in India on an acquisition announcement and the sensitivity of the stock markets during an acquisition announcement. Most of the literature in the West concludes that, on an acquisition announcement, only the targets create value, and the acquirers are value destructive. This study uses a sample of 78 acquirers in the manufacturing industry who acquired targets in the calendar year 2012. The study develops four hypotheses and uses the event study methodology (market model/ ordinary least square model). The results of the study suggest that acquisitions are neither value creative to Indian acquirers and those acquirers with prior acquisition experience create more value than single acquirers. Surprisingly, the results show that acquirers using cash generate negative returns, which may be due to the presence of the hubris effect. Another important finding of the study is that the acquirers using stock as a method of payment are no longer value destructive, which is contrary to the literature which states that acquirers using cash are value creative and acquirers using stock are value destructive. This is an important contribution to the existing literature of the method of payment, and it implies that the theories in the West may not necessarily hold well in India, and they need to be reassessed before being implemented in the Indian context.

Management

Indian Journal of Finance

Do Acquisitions Add Value to Acquirers in India? A Study on the Sensitivity of the Stock Market and Acquirer Returns

World University root node

2014 International Conference on Communication and Signal Processing

Biometric verified access control of critical data on a cloud

The present work deals with the investigation of the corrosion and sliding wear behaviour of detonation gun sprayed (DG) conventional and nanostructured Al2O3-13TiO2 coatings deposited on a biomedical grade Ti-13Nb-13Zr alloy. The microstructure and phase composition of the coatings were characterised by scanning electron microscopy (SEM) and X-ray diffraction (XRD). Hardness measurements were carried out using a Vickers hardness testing machine. The experimental results suggested that the nano structured Al2O3-13TiO2 coating exhibited 43 and 33% increase respectively in corrosion and wear resistances compared to the conventional Al2O3-13TiO2 coating. This improvement in the above properties of nanostructured Al2O 3-13TiO2 coating is due to the presence of larger volume fraction of nanosized particles and lower porosity attained by spraying using DG. © 2014 Institute of Materials, Minerals and Mining.

Department of Control and Automation

School of Electrical Engineering

Surface Engineering

Detonation gun sprayed Al2O3–13TiO2coatings for biomedical applications

Indian Journal of Marketing

Exploring the Dimensions of Pilgrims' Experiences

The Indian Economic Journal

Credit Risk Management in Indian Banks

Diabetes Mellitus and Human Health Care

Review on Novel 2,4-Thiazolidinedione Derivatives as Potential Therapeutic Agents for Type II Diabetes

Biofabrication of CuNps from AmC aqueous leaf extract of various sizes with good anti-inflammatory and mosquito larvicidal efficacy.

RSC Adv.

One-step biofabrication of copper nanoparticles from Aegle marmelos correa aqueous leaf extract and evaluation of its anti-inflammatory and mosquito larvicidal efficacy

A series of 2-(3,5-substituted-1H-pyrazol-1-yl)-3-substituted quinolines 5a–g, were obtained from 2-chloro-3-(1,3-dioxolan-2-yl) quinolines 2a–c and diketones 3a–c with great yields by utilizing Montmorillonite clay K-10 as a catalyst in an eco-friendly methodology. All the synthesized compounds were characterized by FTIR, 1H-NMR, 13C-NMR and HRMS spectral techniques. Antibacterial screening of the compounds revealed that some of the compounds demonstrate moderate to good results. Amongst all, compound 2c displayed a good inhibitory profile against P. aeruginosa and B. subtilis, while compound 5c exhibited remarkable activity against S. aureus, B. subtilis and P. aeruginosa with an MIC value of 25 μg mL−1. Moreover, compound 5c presented a MIC value of 50 μg mL−1 against E. coli and K. pneumoniae, which was comparable to that of the standard. In addition, compound 5f was demonstrated good viability against S. aureus and P. aeruginosa with a MIC value of 25 μg mL−1. Compounds 2c and 5f, however, showed relatively moderate inhibition against S. aureus, while the latter had a moderate activity against B. subtilis. To further demonstrate the antibacterial efficacy of 2c, 5c and 5f, molecular docking studies were done, confirming that compound 5c possesses good binding interaction with the peptide deformylase protein, with a binding energy of −8.1 kcal mol−1—more prominent than that of standard ampicillin (−7.5 kcal mol−1)—while compounds 2c and 5f have moderate binding affinity.

Department of Chemistry

School of Advanced Sciences

Potential anti-bacterial agents: montmorillonite clay-catalyzed synthesis of novel 2-(3,5-substituted-1H-pyrazol-1-yl)-3-substituted quinolines and their in silico molecular docking studies