Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

VIT Unitversity

Department of Commerce

School of Social Sciences & Languages

Vellore Campus

Environmental Science and Engineering Socio-economic and Eco-biological Dimensions in Resource use and Conservation

Biodiversity and Conservation: India’s Panoramic View

The agricultural production in India or any part of the world is depending on various factors like availability of arable land, water resources, climatic and diseasefree conditions etc. To overcome all these issues, plant genetic engineering is playing a vital role and it is considered as second green revolution and wide range of genetically modified organisms (GMO) and genetically modified products (GM products) are available today. Those kinds of modified products are made by the introduction of desired foreign genes to plants resulting in solving problems that could not be solved through classical methods. However, the licit behind the growth of biotechnology in terms of genetically modified crops needs to be addressed, to the world of critics, in perceiving the enduring deliberation on GM crops. The major stigma associated with genetically modified products is that it poses a great danger to the society in a number of ways. The social media created new horizon of people's fantasy and they could be triggered for anything. This study deals with the safety issues and legal aspects of genetically modified organisms and their products. © 2018 World Research Association. All rights reserved.

Research Journal of Chemistry and Environment

Legal and safety issues of genetically modified plants: Environmental concern

Protein–protein interaction (PPI) helps in maintaining the cellular homeostasis. In particular, the homodimeric proteins play a crucial role as cell regulators. Studying the critical functions of each PPI on the living system is very challenging. The mutations in the PPIs have given birth to various diseases including many types of cancers and it has soon become the target for drug discovery. The mutations in IDH1, an asymmetric homodimer in the cytoplasm, leads to various diseases including gliomas. In this study, we have used extensive computational approaches to identify the impact of missense mutations (R132C, R132G, R132H, R132L, R132S, and V178I) occurring in the interacting region of the IDH1 homodimer. By in silico pathogenicity analysis, all the mutations occurring at the positions 132 and 178 were found to be pathogenic and neutral respectively. Furthermore, the mutants R132C and R132G were found to be responsible for increasing the stability, whereas the mutants R132H, R132L, and R132S were found to be responsible for the decrease in stability by stability analysis. R132H, R132L, and R132S mutants exhibited higher destabilization when compared to the structures of R132C and R132G mutants by molecular docking and molecular dynamics analysis. © 2018 Elsevier Inc.

Department of Integrative Biology

School of Bio Sciences and Technology

Advances in Protein Chemistry and Structural Biology Protein-Protein Interactions in Human Disease, Part B

Investigating the Influence of Hotspot Mutations in Protein–Protein Interaction of IDH1 Homodimer Protein: A Computational Approach

Intellectual Property (IP) is subject to limitations and the government can impede with the monopoly rights of the IP owners by issuing compulsory licenses, granting licenses of right and daunting with limits on the ground of public health and morality. In the pursuit called competition and development, it is forgotten that an iota of difference does matter. A general perception or what everyone considers as the seeming definition that poverty is a condition where people's basic needs for food, clothing, and shelter are not being met. But many across the globe have no access to indispensable drugs. One basic reason is of course again poverty, where, in many developing countries, consumers do not have enough purchasing power. Other important factors are inadequate national health, infrastructures and financing systems. The prices of medicines also play a vital role as many people in developing countries have to pay for their own medicines and there are no general health insurance systems. This paper addresses the concerns of patent law in pharma industry growth and its implications in developing countries.

International Journal of Pharma and Bio Sciences

Pharma development and law: Are they parallel?

The Eastern Ghats of India is well known for its wealth of natural vegetation and Shervaroy is a major hill range of the Eastern Ghats of Tamil Nadu. Ethnomedicinal studies in the Eastern Ghats of Tamil Nadu or the Shervaroy Hills have been carried out by various researchers. However, there is not much information available on ethnoveterinary medicine in the Eastern Ghats of India. The aim of this study was to examine the potential use of folk plants as alternative medicine for cattle to cure various diseases in the Shervaroy Hills of the Eastern Ghats. Based on interactions with traditional medicine practitioners, it has been observed that a total of 21 medicinal plants belonging to 16 families are used to cure various diseases such as mastitis, enteritis, arthritis, stomatitis, salivation from the mouth, wounding, and conjunctivitis in animals. It has been observed that the traditional knowledge of ethnoveterinary medicine is now confined only among the surviving older people and a few practitioners in the tribal communities of the Shervaroy Hills. Unfortunately, no serious attempts have been made to document and preserve this immense treasure of traditional knowledge. © 2014 Center for Food and Biomolecules, National Taiwan University.

Department of Biotechnology

Fulltext

Journal of Traditional and Complementary Medicine

Ethnoveterinary medicine of the Shervaroy Hills of Eastern Ghats, India as alternative medicine for animals

2014 International Conference on Data Mining and Intelligent Computing (ICDMIC)

Financial risk modelling in vehicle credit portfolio

This paper reports on an exploratory research work carried out aiming to identify the barriers in the usage of traditional medicines by the holders of the knowledge. The focus is on the usage of the traditional medicines by the homogenous people, Malayali tribe community at Shervaroy hills of Eastern Ghats. Semi-structured interviews were conducted among the tribe community of the area. Where the knowledge has been passed on from generations making the traditional medicinal knowledge strongly imbibed in their culture, the research findings divulged the reasons as to why in spite of having immense knowledge on traditional medicines these tribe community are opting for codified from of medicines. This report also explored the understanding of older generation in the context of holders of the traditional medicinal knowledge among the Malayali tribe community. The conclusion supports the implementation of existing policies stringently with recommendations so as to draw closer towards the three objectives enshrined in the Convention of Biodiversity and Biological Diversity Act, 2002. This paper contributes to the policy makers, pharmaceutical companies, non-governmental organizations and the holders of traditional medicinal knowledge so as to collaborate, in the process, protecting and promoting the traditional knowledge in medicinal plants.

Department of Technology Management

School of Mechanical Engineering

Asian Social Science

Exploring the Fences Pertaining to Non Espousal of Traditional Knowledge Based Medicines at Shervaroy Hills, Eastern Ghats, India

In System on Chip, buses and point to point links are used as a communication infrastructure between one IP to another, but these cannot provide efficient interconnect from performance point of view. So NoC architecture was proposed to provide communication in multiprocessor SoC and overcome the limitations. This paper has implemented a 5-port 32-bit and 64-bit router architecture using wormhole routing technique for 2D-mesh network by using simple deterministic algorithm, flow control and decoding mechanism. In this router, 2 types of crossbar are used named as multiplexer and tri-state buffer matrix for efficient design. Comparisons of area and power are done for these router designs using ASIC tool flow in Cadence using TSMC 90nm and 180nm process technologies. Simulation results are performed in Cadence NC simulator. It is demonstrated that multiplexer router design is more efficient than a matrix router design as area and power increases for matrix design while using same port-width. © 2013 IEEE.

Department of Micro and Nanoelectronics

School of Electronics Engineering

2013 IEEE CONFERENCE ON INFORMATION AND COMMUNICATION TECHNOLOGIES

Area and power efficient network on chip router architecture

This paper discusses the origin of various knowledge sources, the traditional knowledge (TK) in general and the same with respect to medicines, its product value across the globe and the percentage of complementary and alternative medicines (CAM) users in developed countries, where India stands in terms of usage as well as production to foreign markets. Importantly, it examines the socio - economic benefits arising out of the same, India's place in the market at a global level in spite of it being the richest with natural resources as well as vast knowledge assets. The knowledge here is intellectual property. This paper proposes some of the remedies in the protection and rights of the knowledge and the communities which have become of prime importance. Hence there is a need to give priority in controlling this problem of erroneous exploitation of TK in India to the maximum extent possible with various legal and marketing strategies.

World University root node

The socio-economic development of India with respect to benefits from commercial exploitation of traditional medicines and its protection

IOSR journal of VLSI and Signal Processing

Performance analysis of High Speed ADC using SR F/F